Drug composition

Each tablet contains acetylsalicylic acid, 150 mg, plus magnesium oxide, 21 mg and the additives: potato starch, saccharose (17 mg), talc, stearic acid and colloidal silica.

Pharmacological description

When used according to the instructions, acetylsalicylic acid decreases the risk of blood clot forming in vessels through selective inhibition of the synthesis of thromboxane, a potent inducer of platelet aggregation.

Indications for use

In the coronary artery disease and other conditions with increased coagulability of blood; after percutaneous transluminal angioplasty, cardiac infarctions, vascular grafting or valve replacement surgery. Prophylactically in the subjects highly endangered the risk of thromboembolism.

Contraindications

Hypersensivity to salicylates. In children and adolescents with concomitant viral infections (e.g. influenza and varicella). In patients with haemophilia, gastric or duodenal ulceration and women in late pregnancy.

Drug interactions

Acetylsalicylic acid enhances the activity of anticoagulant drugs and in case of concomitant corticosteroid use or alcohol intake it multiplies the risk of gastrointestinal bleeding. It adds to the effects and adverse events of non-steroid anti-inflammatory drugs, and to the effects of sulphonyl carbamide derivatives, methotrexate, sulfonamides (or their derivatives) and of valproic acid. Increases plasma concentrations of digoxin, barbiturates and lithium compounds. Reduces activity of aldosterone antagonists and loop diuretics, antihypertensive drugs and gout-suppression medicines that boost excretion of uric acid.

Package
A packet of 2 blisters, 25 tablets per each; or a phial containing 50 or 100 tablets.

Manufacturer
Chemistry and Pharmacy Cooperative „ESPEFA” in Krakow, ul. J. Lea 208.

Before the use acquaint oneself with the leaflet which contains indications, against the indication, given relating to undesirable workings the and dosage and information relating to the healing product, or consult with doctor or pharmacist.

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